Yes, many road bicycle wheel sets are suitable for tubeless tires. These wheel sets are specifically designed and constructed to be compatible with tubeless tire systems, offering several advantages to cyclists. Tubeless-ready road bike wheel sets possess certain features that allow them to work effectively with tubeless tires:

Rim Design: Tubeless-ready rims have a design that includes a hooked bead or specific shaping to secure the bead of a tubeless tire, preventing air loss.

Tubeless Tape and Sealant Compatibility: These wheel sets are typically accompanied by tubeless rim tape and are designed to work with tubeless sealant, allowing an airtight seal between the tire and the rim.

Airtight Seal: The interaction between the tubeless tire and the rim forms an airtight seal, eliminating the need for an inner tube.

Tire Compatibility: While tubeless-ready road bicycle wheel sets are best used with tubeless tires, many of these wheel sets can also accommodate traditional clincher tires and tubes.

Tubeless systems offer advantages like:

Reduced Risk of Flats: Eliminating the inner tube decreases the likelihood of pinch flats or punctures caused by pinching the tube against the rim.

Lower Rolling Resistance: Tubeless systems often result in reduced rolling resistance as there's no friction between the tire and tube.

Improved Traction and Comfort: Lower tire pressures in a tubeless system can enhance grip and ride comfort, especially on rough surfaces.